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Contraindications include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, severe pancreatitis, or severe kidney disease
In one study published in JAMA, people taking GLP-1 agonists had more than three times the incidence of gastroparesis than those taking an alternative obesity drug, Contrave (bupropion-naltrexone)
We do take extra care with patients who have sulfite sensitivities or who are in chemotherapy
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This reflects its higher receptor binding potency per milligram
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