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Your doctor may suggest an alternative diabetes treatment or advise you to avoid breastfeeding while on this medicine
Although the maximum plasma concentration is lower when compound 2 is administered PO (0.77 M) instead of IP (4.8 M), it is still 4.3-fold higher than LD 50 for ex vivo NTS determined in the commonly used 72 h assay, also indicating that TGR inhibitor 2 is orally bioavailable and the initial prediction of oral bioavailability based on the Lipinski et al
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Gastroprotection should be considered in these higher-risk scenarios according to NICE Clinical Knowledge Summaries guidance
It has the same active ingredient as Mounjaro, tirzepatide, which is FDA-approved for the treatment of type 2 diabetes
GLP analogs should not be used for type 1 diabetes
