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Obesity causes heart attacks, strokes, diabetes, cancer, joint disease, sleep apnea, he said
Think of it like suddenly changing the rules of a complex ecosystemsome species thrive, others struggle, and the whole community dynamic shifts
Joglar JA, Chung MK, Armbruster AL, et al
Furthermore, the agonists of Nrf2, which serve as pivotal upstream regulators of SLC7A11, function as indirect activators of System Xc-, as they regulate SLC7A11 at the transcriptional level rather than directly modifying the functional activity of the complex (139)
doi: 10.1038/s41387-018-0061-x
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