Its unusual for the FDA to go against the recommendations of the Pharmacy Compounding Advisory Committee (PCAC), but it has happened at least once before
More serious B12 deficiencies have the potential to impair heart and neurological function, leading to a wide range of serious symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia and changes in reflexes
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GHK-Cu forms when the tripeptide GHK (glycyl-L-histidyl-L-lysine) binds with copper ions
Carefully remove the central part of the metal cap from the vial and disinfect the upper surface with an alcohol swab
Reference: Japjec M, Horvat Pavlov K, Petrovic A, et al