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Survodutide is an acylated long half-life dual agonist for the GCGR/GLP-1 receptor

AOD 9604 Promotes Cartilage Proliferation and Type II Collagen Synthesis in Osteoarthritic Chondrocytes in vitro Wu X, Brown L, Kasran A, et al

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Glycolysis produces pyruvate, which is converted by lactate dehydrogenase (LDH) to lactate, which is then transported by monocarboxylate transporters (MCT) from astrocytes to neurons

p = 0.04) and trials that compared DPP-4 inhibitors with a placebo or active comparators (N = 53,747