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These results suggest that metformin may slow the progression of OA by attenuating excessive oxidative stress
Beyond its primary role in diabetes management, metformin has recently been associated with anti-inflammatory, anti-aging, anticancer, pro-weight loss, and immunomodulatory effects
Other medications, like GLP-1 receptor agonists (e.g., semaglutide), slow stomach emptying and affect satiety hormones, so the approach can vary depending on the drug
Our study was motivated by the previous observation that mitochondrial muscle diseases cause a secondary NAD + deficiency in the skeletal muscle 15
ALA is a powerful antioxidant that protects the body from cellular damage
doi:10.1002/chem.201100751
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