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PKC will act to oppose the intended functions of the insulin receptor by phosphorylating specific substrates on the receptor, reducing the amount of glucose entering the muscle and decreasing glycogen (stored glucose) synthesis

Louis show in a new study that GLP-1 medications may be effective at treating and preventing substance use disorders across all major addictive substances studied, suggesting these drugs target a common biological pathway underlying addiction

For body recomposition, this mechanism provides a critical advantage because it creates caloric deficit through increased burning rather than decreased intake alone

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