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The lack of FDA approval for cosmetic use reflects insufficient clinical evidence demonstrating safety and efficacy for skin lightening purposes

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The number of DHAR genes in a given species usually lies between 2 and 3 (Table 1)

The injury healing context differs from cosmetic use, and concentration decisions should involve qualified practitioners

Interestingly, although no human trials have been conducted to test its efficacy, at least a few clinics in the US provide oral doses of 5-amino-1MQ to their clientele