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conservative protocols remain at 50 mcg/day

Furthermore, the FDA approvals in 2019 of two peptide drugs targeting melanocortin receptors for the treatment of generalized hypoactive sexual desire disorder (bremelanotide) and erythropoietic protoporphyria-associated phototoxicity (afamelanotide) demonstrate the safety of this class of peptides

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These events are rare and more common in patients with pre-existing risk factors: prior history of pancreatitis, high triglycerides, heavy alcohol use, or genetic predisposition

However, initial cases led by Dr