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Another analysis of 12 studies found that people who took alpha-lipoic acid lost an average of 2.8 pounds (1.27 kg) more than those taking a placebo over an average of 23 weeks ( In short, it seems that alpha-lipoic acid has just a slight effect on weight loss in humans

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10.1016/j.surg.2006.07.038 84 KhederS.SisleyK.HadadS.BalasubramanianS