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Editors note: This article originally appeared in Perio-Implant Advisory , a chairside resource for dentists and hygienists that focuses on periodontal- and implant-related issues

Although this won't happen from just a few cups of tea daily, there have been recent cases where habitually drinking extremely large amounts of tea has caused "fluorosis" causing bone pain and even tooth loss

Relevant for weight loss patients who also have gut issues or connective tissue problems that are limiting their training

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KPV's anti-inflammatory contribution is relevant here: synovial inflammation is a consistent feature of chronic joint stress models, and the reduction of IL-1 and TNF- that KPV demonstrates in cell culture models would be a logical correlate in a joint-stress research context [7]

For preclinical tissue models, stronger evidence would require standardized injury models, blinded outcome assessment, histological confirmation, functional endpoints, and comparison against appropriate positive and negative controls