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Drugs affected by gastric emptying Medications are partially digested in the stomach before being emptied into the small intestine, where most drugs are absorbed

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Seek urgent medical attention if you experience: Persistent high blood glucose readings (above 15 mmol/L) Symptoms of hyperglycaemia that don't improve with treatment Unexplained weight loss or persistent fatigue Diabetic ketoacidosis (DKA) is uncommon in type 2 diabetes but can occur in certain situations, particularly if you have significant insulin deficiency, are taking SGLT2 inhibitors, or have a serious illness

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This catches early absorption changes After each significant weight milestone (every 10-15 pounds lost): Recheck TSH and free T4 Every 3-4 months during active weight loss phase: Full thyroid panel including TSH, free T4, free T3 After weight stabilization: Return to every 6 months for the first year, then annually if stable This is more frequent than most GLP-1 prescribers recommend for non-thyroid patients

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Furat et al

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2021;9(1):22-31 and Supplementary Appendix

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