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A study of plasma and urinary levels of free carnitine and short-chain acyl-carnitines in surgical patients showed that the septic state was associated with increased urinary excretion of free carnitine and lower plasma levels of short-chain acyl-carnitines [101]
These estimates were based on patients with available follow-up weight measurements, representing a subset of the full study population
This advantage is thought to stem from tirzepatides unique ability to activate two hormones instead of just one, enhancing appetite suppression and metabolic benefits
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