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To understand the non-monotone behavior of GSH, it is crucial to consider that there are two incoming fluxes to GSH, GS and GR, and two outgoing fluxes, GPX and a large flux out into the blood [Figure 2B]
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At age 20, plasma levels are approximately 200 ng/mL, but by age 60, they drop to roughly 80 ng/mL
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10.1101/cshperspect.a024224 129 GijselinckI.Van MosseveldeS.Van Der ZeeJ.SiebenA.PhiltjensS.HeemanB.et al
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