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The visible results of inflammation reduction include reduced facial puffiness, improved skin quality (clearer, more even tone, reduced redness), decreased joint swelling and pain, improved eye appearance (reduced under-eye bags and redness), and a general appearance of vitality that people describe as looking younger and healthier

Underlying mechanisms contributing to cardiovascular and renal protection are at least partially different between GLP-1RAs (mainly anti-atherogenic and vascular effects) and SGLT2is (mainly systemic and intrarenal hemodynamic changes)

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This is not always the case