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Needs a much closer look

DOI: 10.1080/10715762.2018.1447670 [26] Ma Y, Gao M, Liu D

Discovered in 2015 by researcher Changhan David Lee and colleagues at the University of Southern California, MOTS-c sits at the intersection of some of the most active areas in longevity science: mitochondrial biology, insulin sensitivity, skeletal muscle metabolism, and the molecular response to exercise

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These GST enzymes catalyze the binding of synthesized glutathione to electrophilic xenobiotics (foreign chemicals), reactive drug metabolites, and environmental toxins, effectively neutralizing their threat

131 Owing to its capacity to repress autophagy at multiple levels, ZKSCAN3 is emerging as a key regulator of cellular catabolism