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The FDA has approved certain medications (Victoza, Ozempic, Trulicity) for cardiovascular risk reduction in patients with established cardiovascular disease and type 2 diabetes, and Wegovy for cardiovascular risk reduction in adults with established cardiovascular disease who have overweight or obesity

Biochem Biophys Res Commun 357(1):187193

10.1128/AAC.01703-20 Antimicrob Agents Chemother

CJC-1295 with ipamorelin: Water retention and mild joint stiffness can occur, particularly at higher doses, reflecting the growth hormone elevation

For now, however, curiosity should be balanced with caution

Sarcopenic obesity: epidemiology, pathophysiology, cardiovascular disease, mortality, and management