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Summary: There is no universal medical requirement to gradually wean off GLP-1 receptor agonists, as they do not typically cause physical dependence or withdrawal symptoms requiring dose tapering

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Vitamin B12 Deficiency: Early Symptoms The body has a store of vitamin B12 in the liver and, as a result, can live for several months or even years without a B12 supply

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Nevertheless, this represents the reality of routine clinical practice in which many patients discontinue their treatment during follow-up