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A 2026 systematic review and meta-analysis published in The BMJ provides the most comprehensive picture to date

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Beyond its well established sensory and analgesic properties, capsaicin enhances sympathetic activity and stimulates thermogenesis in brown and beige adipose tissue as well as skeletal muscle via TRPV1 activation-induced Ca 2+ dependent signaling cascades, leading to increased whole-body energy expenditure, reduced adiposity, and improved lipid profiles (57)

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This article compares these options using published clinical data

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