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The Carnitine Shuttle: Moving long-chain fatty acids in the mitochondria The carnitine shuttle is a three-step transport system that enables long-chain fatty acids to cross the inner mitochondrial membrane for -oxidation

Example: a 5 mg (5,000 mcg) vial reconstituted with 2 mL yields 2,500 mcg/mL

This is not listed on the label but is one of the most clinically significant aspects of these medications

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Transient hypotension or orthostatic dizziness affects roughly 35% of patients, particularly during dose escalation or with volume depletion

The Carnitine Shuttle in Mitochondrial Fatty Acid Oxidation