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Hosseini, B., Saedisomeolia, A., Wood, L

By 2014, the FDA approved the first GLP-1 receptor agonist drug for this purpose

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Both in vitro and in vivo studies have provided evidence that Ex-4 can significantly inhibit breast cancer cell proliferation by suppressing NF-B signaling activation and the expression of its downstream target genes, vascular endothelial growth factor (VEGF) and interleukin-8(IL-8) [55]

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