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ONO-3411 and MK-477 have shown anti-inflammatory activity in mouse models, which appears to be exerted through COX inhibition

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10.1016/j.jaci.2004.04.004

Cultivation and commercial production of Spirulina Commercial Spirulina farming began in the 1970s in Mexico, and today, the AsiaPacific region has witnessed a significant rise in Spirulina production (Ma et al