When they stop, it's not just weight that comes back
10.1038/s41387-018-0017-1 Nutr Diabetes
Zepbound and Mounjaro brief dosing guides Tirzepatide is available in the United States under two brand names, both manufactured by Eli Lilly: Mounjaro FDA-approved to improve blood sugar control in adults with type 2 diabetes, used alongside diet and exercise Zepbound FDA-approved for chronic weight management in adults with obesity, or adults who are overweight with at least one weight-related condition
In receptor binding studies, the affinity of tirzepatide was comparable to that of native GIP for the GIP receptor and approximately fivefold weaker than that of native GLP-1 for the GLP-1 receptor [88]
Constipation: Get things moving again by drinking more water, adding a fiber supplement (like Metamucil), or using a gentle osmotic laxative
This happens because the body fights to return to its original weight