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Patients should be aware that severe or progressive cold intolerance especially when accompanied by significant fatigue, constipation, dry skin, hair loss, or unexplained weight gain despite continued GLP-1 therapywarrants investigation for hypothyroidism or other conditions
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Both amycretin and CagriSema are Novo Nordisk programs targeting the same GLP-1 plus amylin dual pathway, but with fundamentally different molecular strategies
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