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The trade-off is a lower per-capsule dose (Thornes is 175 mg per capsule, compared to 500 mg in standard capsules)

Among participants without diabetes, 63% achieved at least 20% weight loss on the 15 mg dose [3]

Giwercman A, von der Maase H, Berthelsen JG, Rorth M, Bertelsen A, Skakkebaek NE (1991) Localized irradiation of testes with carcinoma in situ: effects on Leydig cell function and eradication of malignant germ cells in 20 patients