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2.2.2 Tumor-associated macrophages (TAMs) Tumor-associated macrophages (TAMs) are significantly infiltrated in ovarian cancer, and the extent of their polarization is tightly tied to the local microenvironment (55)
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Thioredoxin reductase 1 is involved in the reduction of thioredoxin which itself is principally involved in the reduction of oxidized disulfide bonds in proteins
(France) Revenue 2025 (Pharmaceutical drug and vaccine sales): $47.42 billion (43.63 billion) 2024 (Pharmaceutical drug and vaccine sales): $47.32 billion 2023 (Pharmaceutical drug and vaccine sales): $40.56 billion Estimated R&D spend: $8.5 billion Number of employees: 82,880 Revenue per employee: $572,000 Sanofi is a French multinational pharmaceutical company with its headquarters located in Paris, France
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