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This analysis specifically in ARC POMC neurons revealed that leptin receptor-expressing and GLP-1R-expressing neurons are non-overlapping [153], which was confirmed in an independent study using in situ hybridization and transgenic reporter mice [154]
NOVEL AGENTS IN THE MANAGEMENT OF DIABETES AND RISK OF WORSENING DIABETIC RETINOPATHY
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10-Formyltetrahydrofolate dehydrogenase The enzyme 10-formyltetrahydrofolate dehydrogenase (FDH) catalyzes the conversion of 10-formyltetrahydrofolate to tetrahydrofolate, an essential cofactor in the metabolism of nucleic acids and amino acids ( Figure 3 )
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