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A 2024 case series in Journal of Clinical Endocrinology reported that patients receiving combination therapy showed 18% greater fat mass reduction compared to GLP-1 monotherapy, with improved energy scores on validated fatigue assessments (Morrison et al., 2024)

Researchers continue examining its long-term effects on body composition and energy balance

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Anecdotes vs

They can reduce appetite and support blood sugar control, but long term weight loss usually depends on sustainable lifestyle changes alongside medication

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